Demecarium Bromide

Preferred Label : Demecarium Bromide;

NCIt synonyms : Visumiotic; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis(methylcarbamate) (2:1);

NCIt definition : The bromide salt form of demecarium, a quaternary ammonium compound and a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity. This causes contraction of the iris sphincter muscle (producing miosis) and the ciliary muscle (affecting the accommodation reflex). In so doing, this agent increases the outflow of the aqueous humor, thereby reducing intraocular pressure.;

UNII : 61D5V4OKTP;

InChIKey : YHKBUDZECQDYBR-UHFFFAOYSA-L;

CAS number : 56-94-0;

Drug name : Humorsol;

Chemical formula : C32H52N4O4.2Br;

ChEBI ID : CHEBI:4391;

Details

Origin ID

C65367;

UMLS CUI

C0057361;

See also inter- (CISMeF)
- Demecarium (bromide) [ICHI extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Demecarium bromide [ICD-11 Extension code]
- Demecarium bromide (substance) [SNOMED CT concept]
- demecarium bromide [MeSH concept]
- demecarium bromide [SNOMED Notion]
Validated automatic mappings to NTBT
- demecarium [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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