NCIt definition : The hydrochloride salt form of clorprenaline, a beta-2 adrenergic agonist with bronchodilator
activity. Clorprenaline selectively binds to and activates beta-2 adrenergic receptors
in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme
that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine
monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial
smooth muscle. This increases air flow and prevents bronchospasms and may eventually
lead to an improvement of airway function.;