Clenbuterol - CISMeF

Preferred Label : Clenbuterol;

NCIt definition : A substituted phenylaminoethanol and a long-acting beta-2 adrenergic agonist with sympathomimetic activity. Clenbuterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of smooth muscle. In addition, clenbuterol also stimulates central nervous system (CNS), and causes an increase in blood pressure and heart rate due to both beta-2 and beta-1 adrenergic activities. This agent may also exert an anabolic or anti-catabolic effect due to as of yet unidentified mechanisms.;

UNII : XTZ6AXU7KN;

InChIKey : STJMRWALKKWQGH-UHFFFAOYSA-N;

CAS number : 37148-27-9;

Chemical formula : C12H18Cl2N2O;

ChEBI ID : CHEBI:174690;

PubMed : 17449161;

Details

Origin ID

C65335;

UMLS CUI

C0008932;

Currated CISMeF NLP mapping
- Clenbuterol [ICD-11 Extension code]
- Clenbuterol [ICHI extension code]
- Clenbuterol [LOINC component]
- Clenbuterol (substance) [SNOMED CT concept]
- Product containing clenbuterol (medicinal product) [SNOMED CT concept]
- clenbuterol [Substance BNPC]
- clenbuterol [MeSH Descriptor]
- clenbuterol [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clenbuterol [ICD-11 Extension code]
- Clenbuterol [LOINC component]
- Clenbuterol (substance) [SNOMED CT concept]
- Product containing clenbuterol (medicinal product) [SNOMED CT concept]
- clenbuterol [ATC Code]
- clenbuterol [ATC Code]
- clenbuterol [Substance BNPC]
- clenbuterol [MeSH Descriptor]
- clenbuterol [MeSH concept]
Validated automatic mappings to BTNT
- clenbuterol [ATC Code]
- clenbuterol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Clenbuterol Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Clenbuterol Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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