NCIt definition : The hydrochloride salt form of chlorphentermine, a chlorinated analogue of phentermine,
a sympathomimetic amine with central nervous system (CNS) stimulating and anorexic
activity. Chlorphentermine acts by facilitating the release of catecholamines, especially
noradrenaline and dopamine, from nerve terminals in the brain and also inhibits their
uptake. The increase in synaptic concentrations of these catecholamines causes behavioral
changes including an increase in motor activity, mental alertness and excitement,
causes euphoria, and suppresses appetite.;
Semantic type(s)