Cefpodoxime - CISMeF

Preferred Label : Cefpodoxime;

NCIt synonyms : Cefpodoxime Base;

NCIt definition : A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.;

UNII : 7R4F94TVGY;

InChIKey : WYUSVOMTXWRGEK-HBWVYFAYSA-N;

CAS number : 80210-62-4;

Chemical formula : C15H17N5O6S2;

ChEBI ID : CHEBI:3504;

Details

Origin ID

C65305;

UMLS CUI

C0055011;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefpodoxime [MeSH Descriptor]
- Cefpodoxime [LOINC component]
- Cefpodoxime (substance) [SNOMED CT concept]
- Product containing cefpodoxime (medicinal product) [SNOMED CT concept]
- cefpodoxime [ATC Code]
- cefpodoxime [SNOMED Notion]
- cefpodoxime [MeSH concept]
Validated automatic mappings to BTNT
- cefpodoxime [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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