NCIt definition : A broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. Mezlocillin
binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane
of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage
of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This
interrupts the final stage of bacterial cell wall synthesis and results in the weakening
of the bacterial cell wall and eventually causing cell lysis.;