Carprofen - CISMeF

Preferred Label : Carprofen;

NCIt synonyms : (RS)-2-(6-Chloro-9H-carbazol-2-yl)propanoic acid;

NCIt definition : A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities, used exclusively in veterinary medicine. Carprofen inhibits the activity of the enzymes cyclo-oxygenase (COX) I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This inhibits the formation of prostaglandins, by prostaglandin synthase, that are involved in pain, inflammation and fever. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.;

UNII : FFL0D546HO;

InChIKey : PUXBGTOOZJQSKH-UHFFFAOYSA-N;

CAS number : 53716-49-7;

Chemical formula : C15H12ClNO2;

ChEBI ID : CHEBI:364453;

Details

Origin ID

C65290;

UMLS CUI

C0054827;

Automatic exact mappings (from CISMeF team)
- Carprofen [ICHI extension code]
Currated CISMeF NLP mapping
- Carprofen [ICD-11 Extension code]
- Carprofen (substance) [SNOMED CT concept]
- carprofen [MeSH concept]
- carprofen [MeSH Supplementary Concept]
- carprofen, (+-)-isomer [MeSH concept]
See also inter- (CISMeF)
- Product containing carprofen (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Carprofen [ICD-11 Extension code]
- Carprofen (substance) [SNOMED CT concept]
- Product containing carprofen (medicinal product) [SNOMED CT concept]
- carprofen [MeSH Supplementary Concept]
- carprofen [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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