NCIt definition : A synthetic catecholamine with positive chronotropic and inotropic properties, used
in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates
beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing
force of myocardial contraction. By exerting a chronotropic and inotropic effect,
arbutamine mimics the cardiac stress caused by exercise that may prevent adequate
tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients
with coronary artery disease.;