Adalimumab - CISMeF

Preferred Label : Adalimumab;

NCIt synonyms : Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), disulfide with human monoclonal D2E7 light chain, dimer; Adalimumab Biosimilar ABP 501;

NCIt definition : A recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with immunomodulating activity. Upon administration, adalimumab binds to TNF-alpha, thereby preventing its binding to the p55 and p75 TNF cell surface receptors and inhibiting TNF-mediated immune responses. TNF-alpha, a pro-inflammatory cytokine, is upregulated in various autoimmune diseases.;

UNII : FYS6T7F842;

CAS number : 331731-18-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 331731-18-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Humira;

Molecule name : D2E7; LU200134; ABP 501;

Details

Origin ID

C65216;

UMLS CUI

C1122087;

Automatic exact mappings (from CISMeF team)
- Adalimumab [ICD-11 Extension code]
- adalimumab [EMDN type]
- adalimumab [medical devices type]
CISMeF manual mappings
- Adalimumab [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Adalimumab [MeSH Descriptor]
- Adalimumab [LOINC component]
- Adalimumab (substance) [SNOMED CT concept]
- Product containing adalimumab (medicinal product) [SNOMED CT concept]
- adalimumab [ATC Code]
- adalimumab [Substance BNPC]
- adalimumab [International Nonproprietary Name]
- adalimumab [MeSH concept]
Validated automatic mappings to BTNT
- adalimumab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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