Malignant Pancreatic Insulinoma

Preferred Label : Malignant Pancreatic Insulinoma;

NCIt synonyms : Malignant Insulinoma; Pancreatic Insulin Producing Carcinoma; Pancreatic Beta Islet Cell Carcinoma;

NCIt related terms : Beta cell tumor, malignant; Insulinoma, malignant;

NCIt definition : An insulin-producing neuroendocrine tumor arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin. It displays vascular invasion and metastasizes to other anatomic sites.;

Neoplastic status : Malignant;

ICD-O code : 8151/3;

Details

Origin ID

C65186;

UMLS CUI

C4721412;

Currated CISMeF NLP mapping
- Insulinoma, malignant [ICD-O code]
- Insulinoma, malignant (morphologic abnormality) [SNOMED CT concept]
- Malignant insulinoma (disorder) [SNOMED CT concept]
- insulinoma, malignant [SNOMED Notion]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Insulinoma, malignant [ICD-O code]
- Insulinoma, malignant (morphologic abnormality) [SNOMED CT concept]
- Malignant insulinoma (disorder) [SNOMED CT concept]
- insulinoma, malignant [SNOMED Notion]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
disease_excludes_finding
- Absence of a Hormonal Syndrome [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- Hypoglycemia [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Presence of a Hormonal Syndrome [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Beta Cell [NCIt concept]
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Islet Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Islet of Langerhans [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Islet of Langerhans [NCIt concept]
- Pancreas [NCIt concept]
disease_mapped_to_gene
- MEN1 Gene [NCIt concept]
- VHL Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 15q [NCIt concept]
- Gain of Chromosome 9q34 [NCIt concept]
- Loss of Chromosome 11q [NCIt concept]
- Loss of Chromosome 3q [NCIt concept]
- del(1p36) [NCIt concept]

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