Preferred Label : Metolazone;
NCIt synonyms : 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide; 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide; 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone;
NCIt definition : A long acting, quinazoline-based sulfonamide thiazide-like, diuretic. Similar to the
thiazides, metolazone acts on the distal convoluted tubule (DCT) and inhibits the
sodium-chloride symporter, thereby preventing sodium and chloride reabsorption and
excretion of water.;
UNII : TZ7V40X7VX;
InChIKey : AQCHWTWZEMGIFD-UHFFFAOYSA-N;
CAS number : 17560-51-9;
Drug name : Diulo; Mykrox; Zaroxolyn; Xuret; Metenix;
Molecule name : SR-720-22;
Chemical formula : C16H16ClN3O3S;
ChEBI ID : CHEBI:64354;
Codes from synonyms : 32079;
Origin ID : C650;
UMLS CUI : C0025854;
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
concept_is_in_subset