Preferred Label : Glucuronidation Pathway;
NCIt synonyms : Glucuronidation;
NCIt definition : An inactivating and detoxification pathway for a variety of exogenous and endogenous
molecules, including drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids,
glucocorticoids, fatty acid derivatives, retinoids and bile acids. Glucuronic acid
is highly soluble in water and is often linked to poisonous substances to allow for
subsequent elimination and to hormones to allow for easier transport. Also, drugs
are commonly conjugated to glucuronic acid to allow for easier delivery. Excretion
occurs via urine or bile.;
Origin ID : C63811;
UMLS CUI : C1880989;
Automatic exact mappings (from CISMeF team)
Semantic type(s)