" /> Caffeic Acid Phenethyl Ester - CISMeF





Preferred Label : Caffeic Acid Phenethyl Ester;

NCIt synonyms : 2-Phenylethyl 3-(3,4-dihydroxyphenyl)-2-propenoate; 3-(3,4-Dihydroxyphenyl)-2-propenoic Acid, 2-Phenylethyl Ester; CAPE;

NCIt definition : The phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and immunomodulating activities. Upon administration, caffeic acid phenethyl ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).;

UNII : G960R9S5SK;

InChIKey : SWUARLUWKZWEBQ-VQHVLOKHSA-N;

CAS number : 104594-70-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 104594-70-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C17H16O4;

Codes from synonyms : 09056;

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15/05/2024


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