Preferred Label : MAGE-A1, Her-2/neu, FBP Peptides Cancer Vaccine;
NCIt synonyms : MAGE-A1, Her-2/neu, FBP Peptides Ovarian Cancer Vaccine; MAGE-A1 Her-2 neu FBP Peptide Cancer Vaccine;
NCIt definition : A synthetic cancer vaccine comprised of multiple peptides derived from MAGE-1A, Her-2/neu,
and folate binding protein (FBP), with potential immunostimulating and antineoplastic
properties. MAGE-A1, Her-2/neu, and FBP proteins are simultaneously over-expressed
in various cancer cell types, such as epithelial ovarian cancer. The MAGE-A1, Her-2/neu,
FBP peptides cancer vaccine includes the peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377,
MAGE-A1:96-104, and Her-2/neu:754-762. Vaccination with this cancer vaccine may activate
the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing
the corresponding antigens, resulting in tumor cell lysis.;
Origin ID : C62775;
UMLS CUI : C1831955;
Semantic type(s)
- concept_is_in_subset
