HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein - CISMeF
HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain ProteinNCIt concept
Preferred Label : HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein;
NCIt synonyms : DR-4; MHC Class I Antigen DRB1*4; HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain; DR4; HLA-DR4; HLA-DR4 Antigen; HLA Class II Histocompatibility Antigen DRB1-4 Beta Chain Protein;
NCIt definition : HLA class II histocompatibility antigen, DRB1-4 beta chain protein (266 aa, 30 kDa)
is encoded by the human HLA-DRB1 gene. This protein is involved in both antigen presentation
to regulatory T cells and in the immune response. The antigen is frequently typed
for bone marrow and kidney transplantation procedures.;
Alternative definition : NCI-GLOSS: A protein on the surface of certain cells that binds another protein called
TRAIL, which may kill some cancer cells. An increase in the amount or activity of
DR4 on cancer cells may kill more cells.;