BMS-275183 - CISMeF

Preferred Label : BMS-275183;

NCIt definition : An orally available, C-4 methyl carbonate analog of paclitaxel with potential antineoplastic activity. Like paclitaxel, BMS-275183 binds to tubulin and stabilizes microtubules, thereby inhibiting microtubule disassembly which results in cell-cycle arrest at the G2/M phase and an induction of apoptosis.;

UNII : UQC681JJIV;

CAS number : 355113-98-3;

Details

Origin ID

C62639;

UMLS CUI

C1098058;

Currated CISMeF NLP mapping
- BMS-275183 [MeSH concept]
- BMS-275183 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- BMS-275183 [MeSH Supplementary Concept]
- BMS-275183 [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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