18F-FHBG - CISMeF

Preferred Label : 18F-FHBG;

NCIt synonyms : Reporter Probe 18F-FHBG; 9-(4-18F-Fluoro-3-[hydroxymethyl]butyl)guanine; 18F-FHBG;

NCIt related terms : 9-(4-(18F)FLUORO-3-(HYDROXYMETHYL)BUTYL)GUANINE;

NCIt definition : A fluorine-18-labeled acycloguanosine derivative substrate for herpes simplex virus type-1 thymidine kinase (HSV1-tk). 18F-FHBG is used as a reporter probe to image the expression of the herpes simplex virus type-1 thymidine kinase (HSV1-tk) gene in gene transfer therapy. HSV1-tk and HSV1-tk-metabolized 18F-FHBG co-localize, allowing positron emission tomography (PET) localization of HSV1-tk gene-transfected tissue and the assessment of gene transfer efficiency.;

UNII : HAF26OMU2K;

CAS number : 206067-82-5;

Details

Origin ID

C62533;

UMLS CUI

C1453307;

Automatic exact mappings (from CISMeF team)
- 9-(4-fluoro-3-hydroxymethylbutyl)guanine [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- 9-(4-((18)F)fluoro-3-hydroxymethylbutyl)guanine [MeSH concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- 9-(4-((18)F)fluoro-3-hydroxymethylbutyl)guanine [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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