Childhood Brain Anaplastic Astrocytoma

Preferred Label : Childhood Brain Anaplastic Astrocytoma;

NCIt synonyms : Anaplastic Pediatric Brain Astrocytoma; Grade III Pediatric Astrocytoma of the Brain; Grade III Pediatric Astrocytoma of Brain; Grade III Childhood Astrocytic Tumor of Brain; Grade III Pediatric Astrocytic Neoplasm of the Brain; Anaplastic Childhood Astrocytoma of Brain; Grade III Childhood Astrocytic Neoplasm of Brain; Grade III Pediatric Brain Astrocytic Neoplasm; Anaplastic Pediatric Astrocytoma of Brain; Grade III Childhood Brain Astrocytic Neoplasm; Grade III Childhood Astrocytoma of the Brain; Grade III Pediatric Brain Astrocytic Tumor; Anaplastic Childhood Brain Astrocytoma; Grade III Childhood Astrocytic Tumor of the Brain; Anaplastic Childhood Astrocytoma of the Brain; Anaplastic Pediatric Astrocytoma of the Brain; Grade III Childhood Brain Astrocytoma; Grade III Childhood Brain Astrocytic Tumor; Grade III Pediatric Astrocytic Neoplasm of Brain; Grade III Childhood Astrocytoma of Brain; Grade III Pediatric Astrocytic Tumor of the Brain; Grade III Pediatric Astrocytic Tumor of Brain; Grade III Childhood Astrocytic Neoplasm of the Brain; Grade III Pediatric Brain Astrocytoma; Grade 3 Childhood Astrocytic Neoplasm of the Brain; Grade 3 Pediatric Brain Astrocytic Neoplasm; Grade 3 Childhood Brain Astrocytic Tumor; Grade 3 Pediatric Astrocytic Neoplasm of the Brain; Grade 3 Pediatric Brain Astrocytoma; Grade 3 Pediatric Astrocytoma of Brain; Grade 3 Pediatric Astrocytic Tumor of Brain; Grade 3 Pediatric Astrocytoma of the Brain; Grade 3 Childhood Astrocytoma of the Brain; Grade 3 Childhood Astrocytic Tumor of Brain; Grade 3 Childhood Astrocytic Neoplasm of Brain; Grade 3 Childhood Brain Astrocytic Neoplasm; Grade 3 Pediatric Astrocytic Tumor of the Brain; Grade 3 Pediatric Brain Astrocytic Tumor; Grade 3 Pediatric Astrocytic Neoplasm of Brain; Grade 3 Childhood Brain Astrocytoma; Grade 3 Childhood Astrocytic Tumor of the Brain; Grade 3 Childhood Astrocytoma of Brain;

NCIt definition : An anaplastic astrocytoma that arises from the brain and occurs during childhood.;

Neoplastic status : Malignant;

Details

Origin ID

C6252;

UMLS CUI

C1332947;

Disease may have findings
- Headache [NCIt concept]
- Motor Manifestations [NCIt concept]
- Seizure [NCIt concept]
- Sensory Manifestations [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Grade 4 Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Necrotic Change [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Astrocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Childhood Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 6 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Deletion [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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