NCIt definition : A recombinant peptide similar to or identical to endogenous human cytokine interleukin-21
(IL-21) with potential antineoplastic activity. Denenicokin binds to and activates
IL-21 receptors, expressed on T-cells, B-cells, dendritic cells (DC), and natural
killer (NK) cells, modulating the proliferation and/or differentiation of T and B
cells, promoting T cell survival, and increasing the cytolytic activity of cytotoxic
T lymphocytes (CTLs) and NK cells.;
UNII : A4LY1V9F0H;
CAS number : 716840-32-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 716840-32-3
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