Preferred Label : Indium In 111 Chimeric Monoclonal Antibody 806;
NCIt synonyms : Indium 111 Chimeric Monoclonal Antibody 806; 111-Indium-ch806;
NCIt definition : A recombinant chimeric, mouse-human monoclonal antibody IgG1, directed against the
epidermal growth factor receptor (EGFR) and labeled with the radioisotope indium-111,
with potential radioimaging activity. Indium 111 chimeric monoclonal antibody 806
binds to a specific epitope on EGFR-expressing tumor cells, allowing imaging of EGFR-expressing
tumor cells using gamma scintigraphy. EGFR is a receptor tyrosine kinase that is involved
in the regulation of cell growth and is found to be overexpressed on the cell surfaces
of many tumor cell types.;
Origin ID : C62407;
UMLS CUI : C1831858;
Semantic type(s)
- concept_is_in_subset
- has_target
