NCIt definition : The levo-enantiomer of an orally bioavailable polyphenolic aldehyde, derived primarily
from unrefined cottonseed oil, with potential antineoplastic activity. Mimicking the
inhibitory BH3 (Bcl-2 homology 3) domain of endogenous antagonists of Bcl-2, L-gossypol
binds to and inhibits various anti-apoptotic Bcl-2 proteins, which may result in the
inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.
This agent has greater affinity for Bcl-2 proteins than racemic gossypol.;
CAS number : 90141-22-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 90141-22-3
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Currated CISMeF NLP mapping