Trifluoperazine

Preferred Label : Trifluoperazine;

NCIt synonyms : 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine; TFP; Trifluoperazine Base;

NCIt related terms : 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine;

NCIt definition : A phenothiazine derivative and a dopamine antagonist with antipsychotic and antiemetic activities. Trifluoperazine exerts its antipsychotic effect by blocking central dopamine receptors, thereby preventing effects such as delusions and hallucinations caused by an excess of dopamine. This agent also functions as a calmodulin inhibitor, thereby leading to elevation of cytosolic calcium.;

UNII : 214IZI85K3;

InChIKey : ZEWQUBUPAILYHI-UHFFFAOYSA-N;

CAS number : 117-89-5;

Chemical formula : C21H24F3N3S;

ChEBI ID : CHEBI:45951;

Codes from synonyms : 05084;

Details

Origin ID

C62084;

UMLS CUI

C0040979;

Automatic exact mappings (from CISMeF team)
- Trifluoperazine [ICHI extension code]
- Tripartite motif-containing protein 39 [OMIM gene]
- type IV pilus [GO term]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing trifluoperazine (medicinal product) [SNOMED CT concept]
- Trifluoperazine [ICD-11 Extension code]
- Trifluoperazine [LOINC component]
- Trifluoperazine (substance) [SNOMED CT concept]
- trifluoperazine [ATC Code]
- trifluoperazine [Substance BNPC]
- trifluoperazine [MeSH concept]
- trifluoperazine [MeSH Descriptor]
- trifluoperazine [SNOMED Notion]
Validated automatic mappings to BTNT
- trifluoperazine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Trifluoperazine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Trifluoperazine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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