NCIt definition : The sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate
dissociates into sodium cations and citrate anions; organic citrate ions are metabolized
to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration,
the buffering of excess hydrogen ion, the raising of blood pH, and potentially the
reversal of acidosis. In addition, increases in free sodium load due to sodium citrate
administration may increase intravascular blood volume, facilitating the excretion
of bicarbonate compounds and an anti-urolithic effect.;
Alternative definition : NCI-GLOSS: A drug used in the treatment of metabolic acidosis (a disorder in which
the blood is too acidic).;