" /> Pilocarpine - CISMeF





Preferred Label : Pilocarpine;

NCIt synonyms : Pilocarpine Base;

NCIt definition : A natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to eyes, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accommodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor.;

Alternative definition : NCI-GLOSS: A drug used to increase salivation in people who have dry mouth caused by opioids or radiation therapy. Pilocarpine belongs to the family of drugs called alkaloids.;

UNII : 01MI4Q9DI3;

InChIKey : QCHFTSOMWOSFHM-WPRPVWTQSA-N;

CAS number : 92-13-7;

Drug name : Ocusert Pilo;

Chemical formula : C11H16N2O2;

ChEBI ID : CHEBI:8207;

Codes from synonyms : CDR0000045573;

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Keyword's position in hierarchy(ies) : arborescence

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08/05/2025


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