" /> Trientine Hydrochloride - CISMeF





Preferred Label : Trientine Hydrochloride;

NCIt synonyms : N,N-bis (2-aminoethyl)-1,2-ethanediamine Dihydrochloride;

NCIt definition : The hydrochloride salt form of a metal chelating agent with potential anti-angiogenic activity. Trientine chelates excess copper (Cu) ions in the body; the excess copper is subsequently removed from the body through the kidneys. As Cu is an essential cofactor for cuproenzymes, such as superoxide dismutase 1 (SOD1), depletion of copper may inhibit the activation of signal transduction pathways required for cellular proliferation and angiogenesis. In addition, trientine may inhibit copper-induced secretion of interleukin-8 (IL-8).;

UNII : HC3NX54582;

InChIKey : WYHIICXRPHEJKI-UHFFFAOYSA-N;

CAS number : 38260-01-4;

Drug name : Syprine;

Chemical formula : C6H18N4.2HCl;

Codes from synonyms : 50560;

Détails


Vous pouvez consulter :


Nous contacter.
28/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.