Tiotropium Bromide Monohydrate

Preferred Label : Tiotropium Bromide Monohydrate;

NCIt synonyms : 1,4-Dihydro-3,5-Diiodo-1-Methyl-4-Oxopyridine-2,6-Dicarboxylic Acid; 6Beta,7Beta-Epoxy-3Beta-Hydroxy-8-Methyl-1Alpha-H,5Alpha-H-Tropanium Bromide, Di-2-Thienylglycolate Monohydrate;

NCIt definition : The monohydrate bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a long-acting muscarinic receptor antagonist, with bronchodilating activity. Upon inhalation, tiotropium binds to and blocks mainly muscarinic M3 receptors located on smooth muscle cells, thereby preventing smooth muscle contraction.;

UNII : L64SXO195N;

InChIKey : MQLXPRBEAHBZTK-SEINRUQRSA-M;

CAS number : 411207-31-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 411207-31-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Spiriva;

Chemical formula : C19H22NO4S2.Br.H2O;

Details

Origin ID

C61974;

UMLS CUI

C1579389;

Automatic exact mappings (from CISMeF team)
- 1,4-dihydro-3,5-diiodo-1-methyl-4-oxopyridine-2,6-dicarboxylic acid [Substance BNPC]
- tiotropium bromide [MeSH concept]
- uroselectan B [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Tiotropium [NCIt concept]
is_salt_form_of
- Tiotropium [NCIt concept]

Keyword's position in hierarchy(ies) :

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