Orphenadrine - CISMeF

Preferred Label : Orphenadrine;

NCIt definition : A muscarinic antagonist with muscle relaxant activity. Although the mechanism of action has not been determined, orphenadrine appears to block muscarinic acetylcholine receptors as well as N-methyl-D-aspartate (NMDA) receptors in the central nervous system (CNS). This may interfere with the transmission of nerve impulses from the spinal cord to the muscles and may help relax muscles. In addition, orphenadrine exerts antagonistic effects on histamine H1 receptors.;

UNII : AL805O9OG9;

InChIKey : QVYRGXJJSLMXQH-UHFFFAOYSA-N;

CAS number : 83-98-7;

Chemical formula : C18H23NO;

ChEBI ID : CHEBI:7789;

Details

Origin ID

C61868;

UMLS CUI

C0029309;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Orphenadrine [LOINC component]
- Orphenadrine (substance) [SNOMED CT concept]
- Product containing orphenadrine (medicinal product) [SNOMED CT concept]
- orphenadrine [Substance BNPC]
- orphenadrine [MeSH concept]
- orphenadrine [SNOMED Notion]
- orphenadrine [MeSH Descriptor]
Validated automatic mappings to BTNT
- orphenadrine (chloride) [ATC Code]
- orphenadrine (citrate) [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Orphenadrine Citrate [NCIt concept]
- Orphenadrine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Orphenadrine Citrate [NCIt concept]
- Orphenadrine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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