Preferred Label : Olopatadine Hydrochloride;
NCIt synonyms : Dibenz[B,E]Oxepin-2-Acetic Acid, 11-[3-(Dimethylamino)Propylidene]-6,11-Dihydro-,
Hydrochloride, (Z)-;
NCIt definition : The hydrochloride salt form of olopatadine, a dual action selective histamine H1 receptor
antagonist and mast cell stabilizer with anti-allergic activity. Olopatadine stabilizes
mast cells and prevents histamine release from mast cells. In addition, this agent
also blocks histamine H1 receptors, thereby preventing histamine from binding to these
receptors. Both actions prevent the effects of histamine on capillaries, bronchial
smooth muscle, and gastrointestinal (GI) smooth muscle, including histamine-induced
vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic
contraction of GI smooth muscle. This drug also prevents histamine-induced pain and
itching of mucous membranes.;
UNII : 2XG66W44KF;
InChIKey : HVRLZEKDTUEKQH-NOILCQHBSA-N;
CAS number : 140462-76-6;
Drug name : Patanase; Pataday; Patanol;
Molecule name : KW-4679; ALO-4943A;
Chemical formula : C21H23NO3.HCl;
Origin ID : C61867;
UMLS CUI : C0771892;
CISMeF manual mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
