NCIt definition : An amide-type local anesthetic agent. At the injection site, mepivacaine binds to
specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits
both sodium influx and membrane depolarization. This leads to a blockage of nerve
impulse initiation and conduction and results in a reversible loss of sensation. Compared
to other local anesthetics, this agent has a more rapid onset and moderate duration
of action.;