Preferred Label : Lithium Citrate;
NCIt definition : The citrate salt of lithium, a monovalent cation with antimanic activity. Although
the exact mechanism is unclear, lithium might exert its mood-stabilizing effect via
reduction of catecholamine concentration mediated through transneuronal membrane transport
of sodium ion by sodium-potassium-stimulated adenosine triphosphatase (Na-K-ATPase).
Alternatively, lithium may decrease cyclic adenosine monophosphate (cAMP) concentrations,
which would desensitize hormonal-sensitive adenylyl cyclase receptors. Furthermore,
lithium, in recommended dosage, blocks the activity of inositol-1-phosphatase, thereby
resulting in the subsequent decrease of postsynaptic second messengers, diacylglycerol
and inositol triphosphate, that contribute to chronic cell stimulation by altering
electrical activity in the neuron.;
UNII : 5Z6E9K79YV;
InChIKey : HXGWMCJZLNWEBC-UHFFFAOYSA-K;
CAS number : 6080-58-6;
Chemical formula : C6H5O7.3Li.4H2O;
ChEBI ID : CHEBI:64754;
Origin ID : C61812;
UMLS CUI : C0125997;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
