NCIt definition : The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.
Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux
and prevent the initiation and transmission of nerve impulses (stabilizing neuronal
membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic
bupivacaine, levobupivacaine is associated with less vasodilation and has a longer
duration of action.;