Preferred Label : Carbidopa Anhydrous;
NCIt synonyms : L-Carbidopa Anhydrous; Benzenepropanoic Acid, alpha-hydrazino-3,4-Dihydroxy-alpha-methyl-, (S)-;
NCIt definition : The anhydrous, levorotatory isomer of a synthetic hydrazine derivative of the neurotransmitter
dopamine. Carbidopa, a peripheral dopa decarboxylase inhibitor, is used as an adjunct
with levodopa to prevent levodopa degradation to dopamine in extracerebral tissue,
thereby decreasing the peripheral side effects of levodopa. Carbidopa does not penetrate
the blood brain barrier; therefore, it does not interfere with the central nervous
system (CNS) metabolism of levodopa to the active neurotransmitter dopamine which,
in high concentrations in the brain, has anti-parkinsonian effects.;
UNII : KR87B45RGH;
InChIKey : TZFNLOMSOLWIDK-JTQLQIEISA-N;
CAS number : 28860-95-9;
Chemical formula : C10H14N2O4;
ChEBI ID : CHEBI:39585;
Origin ID : C61803;
UMLS CUI : C1881339;
Manual NTBT mappings (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
