Ipratropium - CISMeF

Preferred Label : Ipratropium;

NCIt synonyms : (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane; Ipratropium Cation;

NCIt definition : A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic postganglionic effector cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine (Ach) mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.;

UNII : GR88G0I6UL;

InChIKey : OEXHQOGQTVQTAT-VQCHGODESA-N;

CAS number : 60205-81-4;

Chemical formula : C20H30NO3;

ChEBI ID : CHEBI:5956;

Details

Origin ID

C61794;

UMLS CUI

C0027235;

Automatic exact mappings (from CISMeF team)
- Ipratropium bromide [ICD-11 Extension code]
- Product containing ipratropium (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
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- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
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- Ipratropium Bromide [NCIt concept]
- Ipratropium Bromide Anhydrous [NCIt concept]
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- Ipratropium Bromide [NCIt concept]
- Ipratropium Bromide Anhydrous [NCIt concept]

Keyword's position in hierarchy(ies) :

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