NCIt definition : The methylbromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic
properties. Homatropine methylbromide, a competitive inhibitor of acetylcholine at
the muscarinic receptor, blocks parasympathetic nerve stimulation, thereby inhibiting
pepsin and gastrin secretion. When administered in high doses, this drug produces
inhibitory effects on acetylcholine activity, specifically on smooth muscle located
in the gastrointestinal, biliary, and genitourinary tracts, resulting in an anti-spasmodic
effect.;