NCIt definition : The acetate salt form of ganirelix, a synthetic decapeptide with high antagonistic
activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix
directly competes with the GnRH for receptor binding in the anterior pituitary gland,
thus induces a rapid and reversible suppression of the release of follicle stimulating
hormone (FSH) and luteinizing hormone (LH). This agent is used for the inhibition
of premature LH surges in women undergoing controlled ovarian hyperstimulation, and
in combination with other hormones for retrieval of the mature follicles for in-vitro
fertilization.;