Fosfomycin - CISMeF

Preferred Label : Fosfomycin;

NCIt definition : A phosphoenolpyruvate analogue and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties. Fosfomycin binds to and inactivates the enzyme enolpyruvate transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis and bacterial cell death.;

UNII : 2N81MY12TE;

InChIKey : YMDXZJFXQJVXBF-STHAYSLISA-N;

CAS number : 23155-02-4;

Chemical formula : C3H7O4P;

ChEBI ID : CHEBI:28915;

Details

Origin ID

C61772;

UMLS CUI

C0016610;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Fosfomycin [ICD-11 Extension code]
- Fosfomycin [LOINC component]
- Fosfomycin (substance) [SNOMED CT concept]
- Product containing fosfomycin (medicinal product) [SNOMED CT concept]
- fosfomycin [ATC Code]
- fosfomycin [Substance BNPC]
- fosfomycin [ATC Code]
- fosfomycin [MeSH concept]
- fosfomycin [MeSH Descriptor]
Validated automatic mappings to BTNT
- fosfomycin [ATC Code]
- fosfomycin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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