Fosamprenavir Calcium

Preferred Label : Fosamprenavir Calcium;

NCIt synonyms : GW433908; 908;

NCIt definition : The calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles.;

UNII : ID1GU2627N;

InChIKey : PMDQGYMGQKTCSX-HQROKSDRSA-L;

CAS number : 226700-81-8;

Drug name : Lexiva;

Chemical formula : C25H34N3O9PS.Ca;

Détails

Origin ID

C61771;

UMLS CUI

C1321660;

Automatic exact mappings (from CISMeF team)
- GW-433908 [MeSH concept]
- fosamprenavir [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Fosamprenavir [NCIt concept]
is_salt_form_of
- Fosamprenavir [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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