NCIt definition : The calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency
virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted
to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then
amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic
cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby
leading to the formation of immature non-infectious viral particles.;