" /> Fomivirsen Sodium - CISMeF





Preferred Label : Fomivirsen Sodium;

NCIt synonyms : ISIS 2922;

NCIt definition : The sodium salt form of fomivirsen, an antisense phosphorothioate oligodeoxynucleotide (ODN) with potent antiviral property. Fomivirsen is a 21-nucleotide ODN complementary to mRNA of the immediate-early region 2 of human cytomegalovirus (CMV). Hybridization of this antisense ODN to CMV mRNA prevents RNA transcription from the immediate-early region 2 gene, thereby inhibiting viral replication. In addition, this agent inhibits adsorption of CMV into host cells via a sequence-independent mechanism. Overall, fomivirsen inhibits viral propagation via inhibiting viral replication and viral uptake by host cells, hence delaying progression of CMV-associated retinitis.;

UNII : 3Z6W3S36X5;

CAS number : 160369-77-7;

Drug name : Vitravene;

Chemical formula : C204H243N63O114P20S20.20Na;

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Keyword's position in hierarchy(ies) : arborescence

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09/05/2025


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