Fenoldopam - CISMeF

Preferred Label : Fenoldopam;

NCIt definition : A benzazepine derivative with vasodilatory and antihypertensive properties. Fenoldopam, a dopamine (DA) receptor agonist, binds specifically to peripheral DA1 receptors and to alpha-2 adrenoceptors with moderate affinity. However, this agent exhibits no significant affinity to DA2, other alpha adrenergic, beta adrenergic, muscarinic, or serotonergic receptors. Receptor binding modulates the transmembrane flux of ions, thereby stimulating adenylate cyclase activity, as well as the release of prolactin. This results in vasodilatation, increased renal blood flow thereby enhancing natriuresis and diuresis leading to a lowering in diastolic blood pressure.;

UNII : INU8H2KAWG;

InChIKey : TVURRHSHRRELCG-UHFFFAOYSA-N;

CAS number : 67227-56-9;

Chemical formula : C16H16ClNO3;

ChEBI ID : CHEBI:5002;

Details

Origin ID

C61759;

UMLS CUI

C0060180;

Automatic exact mappings (from CISMeF team)
- Fenoldopam [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Fenoldopam (substance) [SNOMED CT concept]
- fenoldopam [MeSH Descriptor]
- fenoldopam [MeSH concept]
See also inter- (CISMeF)
- Product containing fenoldopam (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fenoldopam (substance) [SNOMED CT concept]
- Product containing fenoldopam (medicinal product) [SNOMED CT concept]
- fenoldopam [ATC Code]
- fenoldopam [MeSH concept]
- fenoldopam [MeSH Descriptor]
Validated automatic mappings to BTNT
- fenoldopam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Fenoldopam Mesylate [NCIt concept]
is_free_acid_or_base_form_of
- Fenoldopam Mesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients