NCIt definition : An antibiotic with bacteriostatic, antimicrobial and antitubercular properties. Ethambutol
interferes with the biosynthesis of arabinogalactan, a major polysaccharide of the
mycobacterial cell wall. It inhibits the polymerization of cell wall arabinan of arabinogalactan
and lipoarabinomannan by blocking arabinosyl transferases and induces the accumulation
of D-arabinofuranosyl-P-decaprenol, an intermediate in arabinan biosynthesis. This
results in halting bacterial growth.;