" /> Ertapenem - CISMeF





Preferred Label : Ertapenem;

NCIt definition : A 1-beta-methyl carbapenem and broad-spectrum beta-lactam antibiotic with bactericidal property. Ertapenem binds to penicillin binding proteins (PBPs) located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition results in a weakening and subsequent lysis of the cell wall leading to cell death of Gram-positive and Gram-negative aerobic and anaerobic pathogens. This agent is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases.;

UNII : G32F6EID2H;

InChIKey : JUZNIMUFDBIJCM-ANEDZVCMSA-N;

CAS number : 153832-46-3;

Chemical formula : C22H25N3O7S;

ChEBI ID : CHEBI:404903;

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08/05/2025


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