Preferred Label : D-Serine;
NCIt related terms : SERINE, D-;
NCIt definition : A non-essential amino acid and dextro isomer of serine with antipsychotic activity.
D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type
glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to
play a major role in pathophysiology of schizophrenia, therefore, administration of
D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies.;
UNII : 1K77H2Z9B1;
InChIKey : MTCFGRXMJLQNBG-UWTATZPHSA-N;
CAS number : 312-84-5;
Chemical formula : C3H7NO3;
NSC code : 77689;
ChEBI ID : CHEBI:16523;
Origin ID : C61739;
UMLS CUI : C1880218;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
