Docetaxel Anhydrous

Preferred Label : Docetaxel Anhydrous;

NCIt definition : The anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death.;

UNII : 699121PHCA;

InChIKey : ZDZOTLJHXYCWBA-VCVYQWHSSA-N;

CAS number : 114977-28-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 114977-28-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : DOCEFREZ;

Chemical formula : C43H53NO14;

NSC code : 628503;

ChEBI ID : CHEBI:4672;

Details

Origin ID

C61734;

UMLS CUI

C0771375;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- docetaxel anhydrous [MeSH concept]
Validated automatic mappings to NTBT
- Docetaxel [MeSH Descriptor]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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