Digitalin - CISMeF

Preferred Label : Digitalin;

NCIt definition : A glycoside compound, extracted from the leaves and seeds of the common foxglove, with anti-arrhythmic property. Digitalin inhibits the enzymatic activity of the sodium-potassium ATPase pump in cardiac tissue, thereby increasing intracellular sodium and calcium levels and providing a positive inotropic effect. This results in increased force of myocardial muscle contraction. This agent also has a vagal effect on the parasympathetic nervous system, and as such slows the ventricular heart rate as well as helps eliminate fluid from body tissues.;

UNII : Q15ECE254B;

InChIKey : CKNOLMVLQUPVMU-YMMLYESFSA-N;

CAS number : 752-61-4;

Chemical formula : C36H56O14;

ChEBI ID : CHEBI:28143;

Details

Origin ID

C61723;

UMLS CUI

C0058012;

CISMeF manual mappings
- Digitalin (e) [ICD-11 Extension code]
Currated CISMeF NLP mapping
- digitalin [Substance BNPC]
- digitalin [MeSH concept]
- digitalin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Digitalin (e) [ICD-11 Extension code]
- digitalin [Substance BNPC]
- digitalin [MeSH concept]
- digitalin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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