Diethylpropion

Preferred Label : Diethylpropion;

NCIt definition : An amphetamine derivative and a sympathomimetic stimulant with anti-obesity and appetite-suppressant properties. Diethylpropion stimulates neurons to release and maintain high levels of catecholamines including dopamine and norepinephrine resulting in a suppression of hunger signals and appetite. This agent may also indirectly affect leptin-neuropeptide Y (NPY) neurotransmission, which exerts control on metabolic processes such as food intake and body weight homeostasis. Via elevated catecholamine, diethylpropion indirectly elevates leptin levels in the brain, which in turn inhibits production of NPY, a potent stimulator of feeding behavior, thereby preventing the initiation of eating, increasing energy expenditure, and decreasing fat storage.;

UNII : Q94YYU22B8;

CAS number : 90-84-6;

Chemical formula : C13H19NO;

ChEBI ID : CHEBI:4530;

Details

Origin ID

C61721;

UMLS CUI

C0012201;

Automatic exact mappings (from CISMeF team)
- Diethylpropion [ICHI extension code]
See also inter- (CISMeF)
- Diethylpropion [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Amfepramone [ICD-11 Extension code]
- Amfepramone (substance) [SNOMED CT concept]
- Diethylpropion [ICD-11 Extension code]
- Diethylpropion [LOINC component]
- Product containing amfepramone (medicinal product) [SNOMED CT concept]
- amfepramone [ATC Code]
- diethylpropion [Substance BNPC]
- diethylpropion [MeSH concept]
- diethylpropion [MeSH Descriptor]
- diethylpropion [SNOMED Notion]
Validated automatic mappings to BTNT
- amfepramone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Diethylpropion Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Diethylpropion Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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