Preferred Label : Limonene, ( )-;
NCIt synonyms : 1-methyl-4-isopropenyl-1-cyclohexene; D-Limonene; (R)-( )-limonene; ( )-limonene; (4R)-1-methyl-4-(1-methylethenyl)cyclohexene; ( )-(R)-4-isopropenyl-1-methylcyclohexene; (R)-4-isopropenyl-1-methylcyclohexene; Limonene, D-; Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (4R)-; ( )-alpha-Limonene;
NCIt related terms : (R)-1-Methyl-4-(1-methylethenyl)cyclohexene; (4R)-1-methyl-4-prop-1-en-2-yl-cyclohexene; Limonene;
NCIt definition : An oral dietary supplement containing a natural cyclic monoterpene, and a major component
of the oil extracted from citrus peels, with potential chemopreventive and antineoplastic
activities. Upon oral administration, D-limonene activates aldehyde dehydrogenase
3A1 (ALDH3A1), thereby decreasing aldehyde level. This may protect salivary stem/progenitor
cells (SSPCs) from toxic aldehydes and prevent or improve radiation-induced xerostomia.
Limonene and its metabolites perillic acid, dihydroperillic acid, uroterpenol and
limonene 1,2-diol may also inhibit tumor growth through inhibition of p21-dependent
signaling and may induce apoptosis via the induction of the transforming growth factor
beta-signaling pathway. In addition, they inhibit post-translational modification
of signal transduction proteins, resulting in G1 cell cycle arrest as well as differential
expression of cell cycle- and apoptosis-related genes.;
Alternative definition : CRCH: A terpene with two isoprene units forming a ring. The chemical structure is
CC1 CCC(CC1)C( C)C.;
UNII : GFD7C86Q1W;
InChIKey : XMGQYMWWDOXHJM-JTQLQIEISA-N;
CAS number : 5989-27-5; 7705-13-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5989-27-5
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 7705-13-7
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : Alda-341; Alda 341;
Chemical formula : C10H16;
ChEBI ID : CHEBI:15382;
Codes from synonyms : 00103;
Origin ID : C61714;
UMLS CUI : C0950252;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
