" /> Lomustine - CISMeF





Preferred Label : Lomustine;

NCIt synonyms : Chloroethylcyclo- hexylnitrosourea; CCNU; Lomustinum; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea; N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea;

NCIt related terms : CeeNU; Chloroethylcyclohexylnitrosourea; 1-Nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-; Cecenu; Belustine;

NCIt definition : A nitrosourea with antineoplastic activity. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : 7BRF0Z81KG;

InChIKey : GQYIWUVLTXOXAJ-UHFFFAOYSA-N;

CAS number : 13010-47-4;

Drug name : Belustin; Cecenu; Lomeblastin; Lucostine; Citostal; Belustine; Lucostin; Prava; CeeNU; Gleostine;

Molecule name : RB-1509; WR-139017;

Chemical formula : C9H16ClN3O2;

NSC code : 79037;

Codes from synonyms : CDR0000046017; NSC0079037; 311;

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30/05/2025


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