NCIt definition : A synthetic mast cell stabilizer with anti-inflammatory activity. Cromolyn probably
interferes with the antigen-mediated calcium ion influx into mast cells. This prevents
mast cell degranulation, resulting in mast cell stabilization and inhibition of the
release of inflammatory mediators, such as histamine and leukotrienes, which are involved
in type I allergic reactions. Cromolyn also prevents inflammatory mediator release
from eosinophils.;