NCIt synonyms : Antibiotic MM 14151; (Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic
acid;
NCIt definition : A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid
contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active
site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics
from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This
agent is used in conjunction with beta-lactamase susceptible antibiotics, such as
penicillins and cephalosporins, to treat infections caused by beta-lactamase producing
organisms.;
UNII : 23521W1S24;
InChIKey : HZZVJAQRINQKSD-PBFISZAISA-N;
CAS number : 58001-44-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 58001-44-8
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Semantic type(s)