NCIt related terms : Chlorprophenpyridamine; Chlorpheniramine;
NCIt definition : A complex of the synthetic alkylamine derivative and histamine-1 (H1) receptor antagonist
chlorpheniramine with sulfonated styrene-divinylbenzene copolymer, with anti-allergic
activity. Upon administration, chlorpheniramine competitively blocks the H1 receptor,
thereby preventing the actions of histamine on capillaries, and the resulting vasodilation
and edema of the respiratory mucosa. Chlorpheniramine also displays anticholinergic
and mild sedative effects.;